CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 76 enrolled
Drug / intervention
Alcohol, ethyl, moderate dose +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04050735
NCT04050735N/ACompleted
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Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection

Brown University·interventional·Posted Aug 8, 2019·Updated Dec 17, 2025

In Brief

A clinical study evaluating Alcohol, ethyl, moderate dose and Placebo for HIV-1-infection and Alcohol Drinking. Completed, enrolled 76 participants across 1 site.

Detailed Summary

This study will examine whether moderate alcohol use in the context of HIV infection exacerbates inflammatory signaling in the immune system and brain. The study will recruit healthy individuals and people living with HIV infection who are otherwise in good health to participate. Participants will complete an experimental protocol that involves controlled alcohol administration and magnetic resonance imaging (MRI). Primary outcomes are plasma biomarkers of inflammation and MRI markers correlated with neuroinflammation. Results will advance understanding of the effects of alcohol use in people living with HIV infection.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV-1-infection, Alcohol Drinking
CountriesUnited States
CollaboratorsNational Institute of General Medical Sciences (NIGMS), The Miriam Hospital

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedAug 8, 2019
Enrollment StartMay 19, 2021
Primary CompletionJul 2, 2024
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 6.9 years ago

Interventions

Alcohol, ethyl, moderate doseother

Moderate oral dose of ethyl alcohol

Placeboother

Placebo beverage