At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia: A Randomized Controlled Pilot Study
In Brief
A Phase 1 clinical trial evaluating Autologous Platelet Rich Plasma Injection, Depo-Medrol and lidocaine, and 1 other intervention for Occipital Neuralgia and Headache. Completed, enrolled 35 participants across 1 site.
Detailed Summary
This study is a randomized controlled trial, assessing the effect of a single platelet rich plasma (PRP) injection in post traumatic (concussive) greater occipital neuralgia. This study will compare the effects of a single PRP injection to injection with steroid and anesthetic. There will also be a third arm to the study, in which patients will receive an injection with normal saline. This study will assess the severity and frequency of headache symptoms before and after receiving the injection.
Study Details
Timeline
Interventions
60mL of blood will be drawn from the antecubital vein and processed via centrifugation. Samples will be centrifuged as per manufacturer instructions, yielding 5mL of PRP.
Steroid injections will be prepared to include 20mg Depo-Medrol and 2mL 2% lidocaine.
2mL normal saline.