CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 763 enrolled
Drug / intervention
tapinarof cream, 1%drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04053387
NCT04053387Phase 3Completed

A Long-Term, Open-Label, Extension Study to Evaluate the Safety and Efficacy of Tapinarof Cream, 1% for the Treatment of Plaque Psoriasis in Adults

Organon and Co·interventional·Posted Aug 12, 2019·Updated Aug 6, 2025

In Brief

A Phase 3 clinical trial evaluating tapinarof cream, 1% for Plaque Psoriasis. Completed, enrolled 763 participants across 104 sites in 2 countries.

Detailed Summary

This is a long-term, open-label, multicenter, study to evaluate the safety and efficacy of topical tapinarof cream, 1% in adults with plaque psoriasis. Subjects in this study completed treatment in 1 of 2 Phase 3 pivotal efficacy and safety studies (Study DMVT-505-3001 or Study DMVT-505-3002). This study will consist of up to 40 weeks of treatment and a 4-week safety follow-up period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
CollaboratorsIQVIA Biotech

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedAug 12, 2019
Enrollment StartAug 13, 2019
Primary CompletionApr 6, 2021
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 6.9 years ago

Interventions

tapinarof cream, 1%drug

Intermittent use of Tapinarof cream, 1%, applied once daily according to PGA score