At a glance
ClinicalIndex Comparison RecordN/ACompleted· 88 enrolled
Drug / intervention
Normal Nicotine Content research cigarettes +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized Trial of Low Nicotine Cigarettes Plus Electronic Cigarettes in Smokers
In Brief
A clinical study evaluating Normal Nicotine Content research cigarettes, High Nicotine e-cigarette, and 2 other interventions for Tobacco Dependence. Completed, enrolled 88 participants across 1 site.
Detailed Summary
This study aims to determine the health effects of very low nicotine content in cigarettes, in conjunction with the availability of nicotine-containing electronic cigarettes (e-cigs) among smokers with mental health conditions (SMHC).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTobacco Dependence
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)
Timeline
N/ACompletedFinished
2020202120222023202420252026
First PostedAug 2019
Enrollment StartJun 2021
Primary CompletionJul 2024
Study CompletionAug 2024
TodayJul 2026
First PostedAug 15, 2019
Enrollment StartJun 1, 2021
Primary CompletionJul 15, 2024
Study CompletionAug 12, 2024
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 6.9 years ago
Interventions
Normal Nicotine Content research cigarettesother
Research cigarettes with 11.6 mg nicotine/cigarette.
High Nicotine e-cigaretteother
E-cigarette containing high nicotine e-liquid
Very Low Nicotine Content research cigarettesother
Research cigarettes with 0.2 mg nicotine/cigarette.
Zero Nicotine e-cigaretteother
E-cigarette containing zero nicotine e-liquid