CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 25 enrolled
Drug / intervention
Nobio composite +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04059250
NCT04059250N/ACompleted

Nobio In Situ Clinical Study - Pilot Study

University of California, San Francisco·interventional·Posted Aug 16, 2019·Updated Mar 12, 2021

In Brief

A clinical study evaluating Nobio composite and traditional composite for Dental Caries and Denture, Partial, Removable. Completed, enrolled 25 participants across 1 site.

Detailed Summary

Nobio has developed dental restorative materials with long term antibacterial properties in order to fight recurrent decay/caries around restorations. These composites with incorporated non-leaching antibacterial agents might overcome the vicious circle of newly developed cavities around freshly placed fillings. The investigators will ask lower partial denture wearers to allow them to place a "gap model" with the Nobio-composite and enamel slab in one denture flange. In the other denture flange a gap model with a standard composite will be placed as control. In the laboratory the investigators will test with established methods for demineralization/caries prevention in the test and control enamel slabs, respectively.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsNobio Ltd.

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedAug 16, 2019
Enrollment StartMay 28, 2019
Primary CompletionMar 10, 2020
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 6.9 years ago

Interventions

Nobio compositedevice

Nobio has developed a bactericidal composite, which does not leak out the bactericidal nano fillers

traditional compositedevice

traditional composite which has no bactericidal activities