CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 38 enrolled
Drug / intervention
endovascular denervation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04060797
NCT04060797N/ACompleted
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Endovascular Denervation Improves Limb Ischemia in Patients With Peripheral Artery Disease (ED-PAD)

Zhongda Hospital·interventional·Posted Aug 19, 2019·Updated May 20, 2024

In Brief

A clinical study evaluating endovascular denervation and PTA for PAD. Completed, enrolled 38 participants across 1 site.

Detailed Summary

Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs. Endovascular arterial denervation (ED) is a minimally invasive technique which could deliver Radiofrequency energy by a multi-electrode catheter to the Lower limb artery to restore Sympathetic activity. The purpose of this study is to evaluate the effects of multi-electrode radiofrequency ablation system on lower limb ischemia with PAD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPAD
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedAug 19, 2019
Enrollment StartAug 23, 2019
Primary CompletionSep 30, 2021
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 6.9 years ago

Interventions

endovascular denervationdevice

Treating with endovascular denervation (EDN) at the site of the iliac artery distal to the superficial femoral artery proximal before balloon dilation or stent implantation

PTAdevice

Treating with balloon dilation or stent implantation which were Percutaneous transluminal angioplasty (PTA)