At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
In Brief
A clinical study evaluating Exercise training for Heart Failure, Diastolic. Completed, enrolled 93 participants across 1 site.
Detailed Summary
The global objective of this study is to determine the mechanisms of exercise intolerance and dyspnea on exertion (DOE) in patients with HFpEF and based on this pathophysiology, test whether specific exercise training programs (whole body vs single leg) will result in improved exercise tolerance.
Study Details
Timeline
Arms & Interventions
HFpEF patients who have a central limitation as the cause of the exercise intolerance randomized to whole body cycle training.
HFpEF patients who have a central limitation as the cause of the exercise intolerance randomized to isolated single leg training.
HFpEF patients who have a peripheral limitation as the cause of the exercise intolerance randomized to whole body cycle training.
HFpEF patients who have a peripheral limitation as the cause of the exercise intolerance randomized to isolated single leg training.
Interventions
Exercise training, either whole body or isolated single leg