CI

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ClinicalIndex Comparison Record
Phase 2Active· 34 enrolled
Drug / intervention
Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatmentdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04071769
NCT04071769Phase 2Active
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Using Xenon MRI to Evaluate the Efficacy of Therapies for Idiopathic Pulmonary Fibrosis

Duke University·interventional·Posted Aug 28, 2019·Updated Jan 2, 2026

In Brief

A Phase 2 clinical trial evaluating Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment for Idiopathic Pulmonary Fibrosis. Active but no longer recruiting, targeting 34 participants across 1 site.

Detailed Summary

The purpose of this study is being done to determine whether magnetic resonance imaging (MRI) using inhaled hyper-polarized 129 Xenon gas can help visualize impaired lung function to detect changes over time in Idiopathic Pulmonary Fibrosis (IPF) patients receiving approved IPF treatments. Participants will undergo an approximately hour long comprehensive MRI protocol, including administration of multiple doses of hyper-polarized 129 Xenon. The subjects will have this initial study prior to initiation of IPF therapies. Then the participants will have repeat studies at 3, 6 and 12 months following the initiation of therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIdiopathic Pulmonary Fibrosis
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
20202021202220232024202520262027202820292030
First PostedAug 28, 2019
Enrollment StartAug 3, 2020
Primary CompletionOct 17, 2024
Study CompletionSep 30, 2029
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 6.8 years ago

Interventions

Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatmentdrug

Whether magnetic resonance imaging (MRI) using inhaled hyper-polarized 129 Xenon gas can help visualize impaired lung function to detect changes over time in Idiopathic Pulmonary Fibrosis (IPF) patients receiving approved IPF treatments