CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 70 enrolled
Drug / intervention
BioRootdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04072926
NCT04072926Early Ph 1Completed
CompareCT.gov

Clinical Research of the Effects of Photodynamic Therapy and Bioceramic Filling of Root Canals on the Healing of Periapical Lesions and the Occurence of Postoperative Pain After Endodontic Retreatment

Medical Innovation Center Wroclaw·interventional·Posted Aug 28, 2019·Updated Jan 19, 2023

In Brief

A Early Phase 1 clinical trial evaluating BioRoot for Apical Periodontitis. Completed, enrolled 70 participants across 1 site.

Detailed Summary

The purpose is to investigate influence of bioceramic filling of the root canal and photodynamic therapy on periapical healing and development of postoperative pain after endodontic retreatment. Patients are divided into two main groups and each of the group is divided into two subgroups. Main groups are patients receiving photodynamic therapy and patients receiving passive ultrasonic irrigation. Each of the main group is divided by the root canal filling material on the AH+ group and BioRoot group.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsApical Periodontitis
CountriesCroatia
CollaboratorsUniversity of Zagreb

Timeline

Early Ph 1CompletedFinished
2020202120222023202420252026
First PostedAug 28, 2019
Enrollment StartOct 16, 2019
Primary CompletionDec 31, 2021
Study CompletionDec 31, 2022
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 6.8 years ago

Interventions

BioRootdrug

Influence of biomaterial BioRoot on periapical healing