CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 377 enrolled
Drug / intervention
Botulinum Toxin Type A +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04073303
NCT04073303Phase 3Completed

BOTOX® (onabotulinumtoxinA) Treatment of Masseter Muscle Prominence: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

AbbVie·interventional·Posted Aug 29, 2019·Updated May 6, 2025

In Brief

A Phase 3 clinical trial evaluating Botulinum Toxin Type A and Placebo for Masseter Muscle Prominence. Completed, enrolled 377 participants across 21 sites in 3 countries.

Detailed Summary

This study is designed to evaluate the safety and effectiveness of administering BOTOX for the treatment of Masseter Muscle Prominence (MMP) in adults.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, China, Taiwan
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedAug 29, 2019
Enrollment StartAug 29, 2019
Primary CompletionNov 10, 2022
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 6.8 years ago

Interventions

Botulinum Toxin Type Abiological

Day 1 Administration of bilateral intramuscular injections into the masseter

Placeboother

Day 1 Administration of bilateral intramuscular injections of placebo (normal saline) into the masseter