CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 238 enrolled
Drug / intervention
Mepolizumab +1 moredrug
Likely dose
Mepolizumab 100mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04075331
NCT04075331Phase 3Completed

A Randomised Controlled Trial of Mepolizumab Initiated Following Admission to Hospital for a Severe Exacerbation of Eosinophilic COPD

University of Leicester·interventional·Posted Aug 30, 2019·Updated Apr 24, 2026

In Brief

A Phase 3 clinical trial evaluating Mepolizumab and Placebo for COPD and Eosinophilia. Completed, enrolled 238 participants across 1 site.

Detailed Summary

This is a single-centre, double-blinded, randomised, placebo controlled trial comparing mepolizumab 100mg versus placebo in patients with eosinophilic COPD, started following their index admission to hospital.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOPD, Eosinophilia
CountriesUnited Kingdom
CollaboratorsGlaxoSmithKline

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedAug 30, 2019
Enrollment StartSep 7, 2020
Primary CompletionJun 21, 2024
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 6.8 years ago

Interventions

Mepolizumabdrug

Mepolizumab 100mg subcutaneous injection

Placebodrug

Saline solution for subcutaneous injection