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ClinicalIndex Comparison Record

N/ACompleted· 333 enrolled

Drug / intervention

Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring +1 moreother

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

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NCT04077294N/ACompleted

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Epidemiological Patterns, Management Strategies and Cost Analysis of Care for the Patient With Perioperative Myocardial Injury When BNP is Used as a Screening Tool for Non-Cardiac Surgery

University of Alberta·observational·Posted Sep 4, 2019·Updated Jul 28, 2022

In Brief

An observational study evaluating Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring and Use of traditional perioperative cardiac risk stratification only for Myocardial Infarction Postoperative and 2 related conditions. Completed, enrolled 333 participants across 1 site.

Detailed Summary

Recently, the use of preoperative BNP as a preoperative risk stratifcation tool was added to the Canadian Cardiovascular Society (CCS) guidelines (4) on perioperative cardiac risk assessment and management for patients who undergo noncardiac surgery, based on the prognostic value of preoperative BNP in indentifiy patients at significant risk of 30-day mortality, nonfatal myocardial infarction, or myocardial injury after noncardiac surgery (MINS). While the value of screening for high risk patients through the use of preoperative BNP been demonstrated, the management of postoperative ischemia is less clear. Therefore, this study aims to: 1. Evaluation of the use of BNP as a preoperative screening biomarker; how often is it ordered in Anesthesia Preadmission Clinic and what is the incidence of a positive result (BNP ≥ 92 ng/L) 2. Determine the incidence of myocardial injury after non-cardiac surgery (MINS) at 30 days and myocardial infarction at 1 year at a tertiary care center when BNP is used as a screening tool 3. Record patterns of management of patients with MINS 4. Determine the cost associated with the different patterns of management of MINS 5. Comparison with a cohort group who qualified for BNP screening according to CCS guidelines but did not have it measured. The investigators will attempt to evaluate the cohort group for MINS at 30 days and myocardial infarction at 1 year.

Study Details

Study Typeobservational

Allocation--

Masking--

Primary Purpose--

ConditionsMyocardial Infarction Postoperative, Myocardial Injury, Death, Cardiac

CountriesCanada

Collaborators--

Timeline

N/ACompletedFinished

2020202120222023202420252026

Enrollment StartMay 2019

First PostedSep 2019

Primary CompletionSep 2019

TodayJul 2026

First PostedSep 4, 2019

Enrollment StartMay 21, 2019

Primary CompletionSep 12, 2019

TodayJul 2, 2026

Enrollment to primary: 4 monthsPosted 6.8 years ago

Interventions

Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoringother

Patients undergoing non-cardiac surgery risk stratified using BNP measurements according to CCS guidelines.

Use of traditional perioperative cardiac risk stratification onlyother

Patients undergoing non-cardiac surgery risk stratified using tools other than BNP measurement such as revised cardiac risk index (RCRI).