CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 166 enrolled
Drug / intervention
HRHA +3 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04084561
NCT04084561N/ACompleted

Nicotine Dependence and Lung Cancer Genetics in African Americans

Temple University·interventional·Posted Sep 10, 2019·Updated Dec 18, 2023

In Brief

A clinical study evaluating HRHA, LRLA, and 2 other interventions for Lung Cancer. Completed, enrolled 166 participants across 2 sites.

Detailed Summary

The study aims to understand the effects of learning about one's genetic risk for lung cancer that is specific to their ancestry. Participants will be given hypothetical personalized genetic risk results and ask to think about how they might respond to such information if they actually received such results.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLung Cancer
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedSep 10, 2019
Enrollment StartSep 1, 2018
Primary CompletionApr 1, 2022
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 6.8 years ago

Interventions

HRHAbehavioral

participants will be asked to consider a hypothetical scenario in which genetic test results reveal that: 1) they carry genotypes that place African American smokers at a particularly high (\~50%-80%) risk for the development of lung cancer, and 2) their genetic profile reflects a particularly high concordance with African heritage (\~90%).

LRLAbehavioral

participants will be asked to consider a scenario in which genetic test results reveal that: 1) they are at normal (\~7%-10%) risk for the development of lung cancer, and 2) their genetic profile reflects a particularly low concordance with African heritage (\~10%).

HRLAbehavioral

participants will receive "High Risk, Low Ancestry (HRLA)" hypothetical

LRHAbehavioral

participants will receive "Low Risk, High Ancestry (HRLA)" hypothetical