CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 26 enrolled
Drug / intervention
Paired-Associative Stimulation (PAS) +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04088565
NCT04088565N/ACompleted
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Mechanisms of Non-invasive Vagus Nerve Stimulation Underlying Enhanced Motor Control in Humans

University of Pittsburgh·interventional·Posted Sep 13, 2019·Updated Nov 1, 2022

In Brief

A clinical study evaluating Paired-Associative Stimulation (PAS), Vagus Nerve Stimulation (VNS), and 1 other intervention for Stroke. Completed, enrolled 26 participants across 1 site.

Detailed Summary

The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedSep 13, 2019
Enrollment StartSep 22, 2019
Primary CompletionNov 9, 2021
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 6.8 years ago

Interventions

Paired-Associative Stimulation (PAS)other

Simultaneous activation of connections in motor cortex via stimulation to the nerves and brain.

Vagus Nerve Stimulation (VNS)other

Recruits the auricular branch of the vagus nerve which activates brain structures that release chemicals mediating cortical plasticity.

Sham Stimulationother

Sub-threshold stimulation that does not activate neural structures.