CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,430 enrolled
Drug / intervention
Herpes Zoster subunit (HZ/su) vaccine (GSK1437173A) +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04091451
NCT04091451Phase 3Completed

A Phase III, Randomized, Observer-blind, Placebo Controlled, Multicenter Clinical Trial to Assess Herpes Zoster Recurrence and the Reactogenicity, Safety and Immunogenicity of GSK Biologicals' Herpes Zoster Vaccine (HZ/su) When Administered Intramuscularly on a 0 and 2 Month Schedule to Adults ≥50 Years of Age With a Prior Episode of Herpes Zoster

GlaxoSmithKline·interventional·Posted Sep 16, 2019·Updated Dec 4, 2025

In Brief

A Phase 3 clinical trial evaluating Herpes Zoster subunit (HZ/su) vaccine (GSK1437173A) and Placebo for Herpes Zoster. Completed, enrolled 1,430 participants across 3 sites.

Detailed Summary

The purpose of this study was to assess the safety and immunogenicity of GSK Biologicals' HZ/su vaccine when given on a two-dose schedule to adults aged 50 years and above who had a previous episode of Herpes Zoster (HZ).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHerpes Zoster
CountriesRussia
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedSep 16, 2019
Enrollment StartSep 17, 2019
Primary CompletionFeb 15, 2024
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 6.8 years ago

Interventions

Herpes Zoster subunit (HZ/su) vaccine (GSK1437173A)biological

2 doses of HZ/su vaccine were administered intramuscularly according to a 0,2 months vaccination schedule, at Day 1 and Month 2.

Placebodrug

2 doses of Placebo were administered intramuscularly according to a 0,2 months vaccination schedule, at Day 1 and Month 2.