At a glance
ClinicalIndex Comparison RecordN/ACompleted· 11 enrolled
Drug / intervention
PET/MRIother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Determining the Magnitude of Early Steps of Fatty Acid Oxidation in Glioma Using 18F-FPIA
In Brief
An observational study evaluating PET/MRI for Glioma. Completed, enrolled 11 participants across 1 site.
Detailed Summary
Glioma is the most common primary malignant brain tumour in adults and has an extremely poor prognosis. The aim of this study is to quantify the degree of early step fatty acid oxidation in gliomas as imaged by 18F-FPIA PET/MRI in 10 evaluable patients. The Investigators hypothesise that FPIA uptake will be higher in high-grade gliomas compared to lower grade gliomas, in keeping with a higher propensity of high grade tumours to generate ATP and NADPH via fatty acid oxidation under bioenergetic stress.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsGlioma
CountriesUnited Kingdom
Collaborators--
Timeline
N/ACompletedFinished
20192020202120222023202420252026
Enrollment StartDec 2018
First PostedSep 2019
Primary CompletionAug 2020
TodayJul 2026
First PostedSep 20, 2019
Enrollment StartDec 6, 2018
Primary CompletionAug 7, 2020
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.8 years ago
Interventions
PET/MRIother
Imaging scan