CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 104 enrolled
Drug / intervention
Gaboxadol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04106557
NCT04106557Phase 3Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study to Evaluate the Efficacy and Safety of OV101 in Pediatric Individuals With Angelman Syndrome

Healx AI·interventional·Posted Sep 27, 2019·Updated Jan 8, 2024

In Brief

A Phase 3 clinical trial evaluating Gaboxadol and Placebo for Primary Disease or Condition Being Studied: Angelman Syndrome (AS). Completed, enrolled 104 participants across 14 sites in 5 countries.

Detailed Summary

The purpose of this study is to assess the efficacy and safety of oral OV101 (gaboxadol) in pediatric subjects with Angelman syndrome.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Germany, Israel, Netherlands, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedSep 27, 2019
Enrollment StartSep 9, 2019
Primary CompletionNov 2, 2020
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 6.8 years ago

Interventions

Gaboxadoldrug

OV101 versus placebo once daily at bedtime for 12 weeks

Placebodrug

Matching placebo capsules to OV101 capsules.