CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
GnRh antagonist +1 moredrug
Likely dose
GnRh antagonist 0.25 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04108039
NCT04108039N/ACompleted
CompareCT.gov

Suppression of Endogenous Luteinizing Hormone (LH) Surge With Progesterone vs GnRH Antagonist in Freeze-all IVF Cycles. A Prospective Equivalence Study With Repeated Ovarian Stimulation Cycles.

Fundacion Dexeus·interventional·Posted Sep 27, 2019·Updated May 15, 2023

In Brief

A clinical study evaluating GnRh antagonist and Micronized progesterone for Infertility and 2 related conditions. Completed, enrolled 44 participants across 1 site.

Detailed Summary

To examine whether the number of euploid embryos following ovarian stimulation with micronized progesterone is equivalent as compared with the number of embryos after ovarian stimulation with the use of a GnRH antagonist in patients undergoing ovarian stimulation for IVF or intracytoplasmatic sperm injection (ICSI).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfertility, IVF, Preimplantation Diagnosis
CountriesSpain
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedSep 27, 2019
Enrollment StartSep 25, 2019
Primary CompletionJan 15, 2022
Study CompletionMay 15, 2022
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 6.8 years ago

Interventions

GnRh antagonistdrug

In the antagonist cycle, LH suppression will be accomplished by subcutaneous (SC) injections of 0.25 mg of Cetrorelix or Ganirelix starting in the presence of follicles \>14mm or E2 levels \>400 pg/ml and continuing until ovulation triggering to avoid LH surge in COS

Micronized progesteronedrug

Micronized progesterone protocol to avoid LH surge in COS, from stimulation day 1 and continuing until ovulation triggering.