CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 406 enrolled
Drug / intervention
S-600918 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04110054
NCT04110054Phase 2Completed

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-selection Study of S-600918 in Patients With Refractory Chronic Cough

Shionogi·interventional·Posted Oct 1, 2019·Updated Mar 27, 2024

In Brief

A Phase 2 clinical trial evaluating S-600918 and Placebo to S-600918 for Chronic Cough. Completed, enrolled 406 participants across 136 sites in 6 countries.

Detailed Summary

The primary objective of this study is to determine the optimal dose of S-600918 in patients with refractory chronic cough by evaluating the change from baseline in 24-hour cough frequency (coughs per hour) with S-600918 compared with placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Cough
CountriesCzechia, Japan, Poland, Ukraine, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedOct 1, 2019
Enrollment StartFeb 13, 2020
Primary CompletionDec 8, 2020
Study CompletionDec 28, 2020
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 6.8 years ago

Interventions

S-600918drug

Tablets for oral administration

Placebo to S-600918drug

Tablets for oral administration