At a glance
ClinicalIndex Comparison RecordN/ACompleted· 513 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome
In Brief
An observational study for Acute Respiratory Distress Syndrome. Completed, enrolled 513 participants across 16 sites.
Detailed Summary
The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Respiratory Distress Syndrome
CountriesUnited States
CollaboratorsAkron Children's Hospital, Children's Hospital and Health System Foundation, Wisconsin, Children's Hospital Medical Center, Cincinnati, Children's Mercy Hospital Kansas City, Milton S. Hershey Medical Center, Nationwide Children's Hospital, Nicklaus Children's Hospital, Indiana University, Cooperman Barnabas Medical Center, Baylor College of Medicine, Columbia University, National Heart, Lung, and Blood Institute (NHLBI), Arkansas Children's Hospital Research Institute, Children's Healthcare of Atlanta, Children's Hospital Colorado, Washington University School of Medicine
Timeline
N/ACompletedFinished
2020202120222023202420252026
First PostedOct 2019
Enrollment StartJan 2020
Primary CompletionFeb 2025
Study CompletionApr 2025
TodayJul 2026
First PostedOct 2, 2019
Enrollment StartJan 7, 2020
Primary CompletionFeb 15, 2025
Study CompletionApr 1, 2025
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 6.8 years ago