At a glance
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The Effects of Topical Corticosteroid Use on Insulin Sensitivity and Bone Turnover
In Brief
A Phase 4 clinical trial evaluating Betnovate, betamethasone dipropionate ointment 0.1% and placebo and Protopic, tacrolimus ointment 0.1% for Atopic Dermatitis and Atopic Eczema. Completed, enrolled 36 participants across 1 site.
Detailed Summary
The investigators believe that the emerging epidemiological evidence connecting topical use of corticosteroids to the development of type 2 diabetes and osteoporosis point to potentially massive, yet clinically unacknowledged problems associated with topical corticosteroid treatment. Using state-of-the-art methodology, the present study will delineate the impact of topical corticosteroid use on insulin sensitivity and bone turnover markers in patients with atopic dermatitis and, thus, provide important data that may have implications for millions of people using topical corticosteroids.
Study Details
Timeline
Interventions
Explore the systemic effects of Betnovate
Compare the systemic effects of Betnovate to Protopic