CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Standard Carb Diet +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04118374
NCT04118374N/ACompleted

A Study to Determine Iatrogenic Hyperinsulinemia's Contribution to Insulin Resistance and Endothelial Dysfunction in Type 1 Diabetes

Vanderbilt University Medical Center·interventional·Posted Oct 8, 2019·Updated Oct 28, 2025

In Brief

A clinical study evaluating Standard Carb Diet and Low Carb Diet for Diabetes Mellitus, Type 1. Completed, enrolled 14 participants across 1 site.

Detailed Summary

The investigators will test the hypothesis that reducing insulin doses using a low carbohydrate diet (LCD) will be associated with with improved insulin sensitivity (Aim 1) and blood vessel health (Aim 2).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedOct 8, 2019
Enrollment StartNov 24, 2021
Primary CompletionJun 21, 2024
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 6.7 years ago

Interventions

Standard Carb Dietother

Approximately 50% of caloric intake will come from carbohydrate consumption.

Low Carb Dietother

Approximately 25% of caloric intake will come from carbohydrate consumption.