CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 95 enrolled
Drug / intervention
FX-322 (One Dose) +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04120116
NCT04120116Phase 2Completed

A Phase 2a, Prospective, Randomized, Double-Blind, Placebo-Controlled, Single and Repeat-Dose, Multicenter, Exploratory Efficacy Study of FX-322 Administered by Intratympanic Injection in Adults With Stable Sensorineural Hearing Loss

Frequency Therapeutics·interventional·Posted Oct 9, 2019·Updated Apr 27, 2023

In Brief

A Phase 2 clinical trial evaluating FX-322 (One Dose), FX-322 (Two Doses), and 2 other interventions for Sensorineural Hearing Loss and 2 related conditions. Completed, enrolled 95 participants across 16 sites.

Detailed Summary

This is a phase 2a single and repeat dose exploratory efficacy study of intratympanic FX-322 compared to placebo in healthy male and female adults with stable sensorineural hearing loss.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedOct 9, 2019
Enrollment StartOct 4, 2019
Primary CompletionOct 6, 2020
Study CompletionDec 17, 2020
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 6.7 years ago

Interventions

FX-322 (One Dose)drug

Patients will receive one dose of FX-322.

FX-322 (Two Doses)drug

Patients will receive two doses of FX-322.

FX-322 (Four Doses)drug

Patients will receive four doses of FX-322.

Placebodrug

Patients will receive Placebo.