At a glance
ClinicalIndex Comparison RecordN/ACompleted· 326 enrolled
Drug / intervention
Preventive Conditioned NIV Therapy after planned extubation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation on Reintubation in Obese or High-Risk Patients. A Randomized Clinical Trial.
In Brief
A clinical study evaluating Preventive Conditioned NIV Therapy after planned extubation and Preventive HFOT after planned extubation for Extubation Failure. Completed, enrolled 326 participants across 2 sites.
Detailed Summary
The main aim is to demonstrate whether reintubation rate is lower with preventive conditioned noninvasive ventilation (NIV) rather than with High-flow oxygen therapy (HFOT) in obese intermediate-risk patients and in high-risk patients.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsExtubation Failure
CountriesSpain
Collaborators--
Timeline
N/ACompletedFinished
2020202120222023202420252026
First PostedOct 2019
Enrollment StartJun 2020
Primary CompletionJun 2021
Study CompletionDec 2021
TodayJul 2026
First PostedOct 14, 2019
Enrollment StartJun 1, 2020
Primary CompletionJun 1, 2021
Study CompletionDec 1, 2021
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 6.7 years ago
Interventions
Preventive Conditioned NIV Therapy after planned extubationdevice
Conditioned NIV during 48 hours following extubation.
Preventive HFOT after planned extubationdevice
HFOT set according to patients tolerance during 48 hours following extubation