CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 6 enrolled
Drug / intervention
Lofexidine Oral Tabletdrug
Likely dose
Lofexidine Oral Tablet 0.54 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04126083
NCT04126083Phase 4Completed
CompareCT.gov

Lofexidine for Rapid Pre-Operative Opioid Tapering in Adults Undergoing Lumbar Spine Surgery

Mayo Clinic·interventional·Posted Oct 15, 2019·Updated Feb 23, 2022

In Brief

A Phase 4 clinical trial evaluating Lofexidine Oral Tablet for Opioid Withdrawal. Completed, enrolled 6 participants across 1 site.

Detailed Summary

The primary objective is to investigate the effects of lofexidine in adults undergoing opioid tapering prior to elective lumbar spine surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOpioid Withdrawal
CountriesUnited States
CollaboratorsUSWM, LLC (dba US WorldMeds)

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedOct 15, 2019
Enrollment StartSep 1, 2019
Primary CompletionApr 15, 2021
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 6.7 years ago

Interventions

Lofexidine Oral Tabletdrug

lofexidine 0.54 mg 4 times daily