CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 183 enrolled
Drug / intervention
VIB4920 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04129164
NCT04129164Phase 2Completed

A Phase 2 Randomized, Double-blind, Placebo-controlled, Proof of Concept Study to Evaluate the Efficacy and Safety of VIB4920 in Subjects With Sjögren's Syndrome (SS)

Amgen·interventional·Posted Oct 16, 2019·Updated Apr 30, 2025

In Brief

A Phase 2 clinical trial evaluating VIB4920 and Placebo for Sjögren's Syndrome. Completed, enrolled 183 participants across 62 sites in 12 countries.

Detailed Summary

The purpose of the study is to evaluate the efficacy, safety, and tolerability of VIB4920 (formerly MEDI4920) in adult participants with Sjögren's Syndrome (SS).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, France, Hungary, India, Italy, Mexico, Peru, Poland, South Korea, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedOct 16, 2019
Enrollment StartDec 9, 2019
Primary CompletionSep 1, 2022
Study CompletionMar 10, 2023
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 6.7 years ago

Interventions

VIB4920drug

Intravenous Dose 1.

Placebodrug

Intravenous dose matched to VIB4920.