CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 20 enrolled
Drug / intervention
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) + Task Specifc Trainingdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04129242
NCT04129242Early Ph 1Completed

Optimization of Closed-loop Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) as a Neurorehabilitation Tool

Medical University of South Carolina·interventional·Posted Oct 16, 2019·Updated Feb 28, 2024

In Brief

A Early Phase 1 clinical trial evaluating Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) + Task Specifc Training for Stroke. Completed, enrolled 20 participants across 1 site.

Detailed Summary

This study explores the use of a new form of neuromodulation known as transcutaneous auricular vagus nerve stimulation (taVNS) which stimulates the ear. This stimulation will be delivered concurrently with upper limb motor rehabilitation training (3 days/week for 4 weeks) in chronic stroke patients. Patients will undergo a series of baseline assessments (including a brain scan), a 4-week course of motor rehabilitation, and post-assessments (including a second brain scan)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke
CountriesUnited States

Timeline

Early Ph 1CompletedFinished
2020202120222023202420252026
First PostedOct 16, 2019
Enrollment StartFeb 19, 2020
Primary CompletionOct 5, 2022
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 6.7 years ago

Interventions

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) + Task Specifc Trainingdevice

A closed-loop taVNS system that delivers taVNS with upper-limb rehabilitation training in a chronic stroke population.