CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 12 enrolled
Drug / intervention
Transcranial Magnetic Stimulation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04130646
NCT04130646N/ACompleted
CompareCT.gov

Combining Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Transcranial Magnetic Stimulation (TMS) to Enhance Cortical Excitability

Medical University of South Carolina·interventional·Posted Oct 17, 2019·Updated Apr 20, 2025

In Brief

A clinical study evaluating Transcranial Magnetic Stimulation and transcutaneous auricular vagus nerve stimulation (taVNS) for Stroke and 2 related conditions. Completed, enrolled 12 participants across 1 site.

Detailed Summary

Transcranial Magnetic Stimulation (TMS) positively influences motor rehabilitation in stroke recovery. Transcutaneous auricular vagus nerve stimulation (taVNS) has shown effects on cortical plasticity. We investigate whether combination of TMS and taVNS is more effective at motor cortex excitability than either modality alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke, Stroke Sequelae, Motor Activity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedOct 17, 2019
Enrollment StartMar 15, 2020
Primary CompletionJun 12, 2023
Study CompletionDec 6, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 6.7 years ago

Interventions

Transcranial Magnetic Stimulationdevice

transcranial magnetic stimulation delivers magnetic pulses to the brain through the scalp/skull

transcutaneous auricular vagus nerve stimulation (taVNS)device

non-invasive vagus nerve stimulation delivers electricity to the ear