CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Ridge preservation using L-PRF/FDBA layered technique +2 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04133363
NCT04133363N/ACompleted
CompareCT.gov

Clinical, Radiographic, and Histomorphometric Outcomes Following Ridge Preservation Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-Dried Bone Allograft (FDBA) Layered Technique: A Prospective, Randomized Clinical Trial

University of Alabama at Birmingham·interventional·Posted Oct 21, 2019·Updated Sep 26, 2024

In Brief

A clinical study evaluating Ridge preservation using L-PRF/FDBA layered technique, Ridge preservation using L-PRF/FDBA, and 1 other intervention for Ridge Preservation. Completed, enrolled 30 participants across 1 site.

Detailed Summary

This study will evaluate the effect of Leukocyte Platelet Rich Fibrin and freeze-dried bone allograft in a layered technique on the bone quantity and quality following socket grafting in preparation for endosseous implant placement. Pre (baseline)- and post-grafting (3 months) clinical as well as 2- and 3-dimensional radiographic measurements will be used to evaluate the dimensional ridge changes between sites grafted with L-PRF/FDBA layered technique vs. L-PRF/FDBA and L-PRF alone. Histological analysis will be performed by a bone biopsy taken at time of surgical re-entry (after 3 months) of grafted sites to place the dental implant and assessed for differences in new bone formation between the three types of graft.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRidge Preservation
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedOct 21, 2019
Enrollment StartJun 15, 2020
Primary CompletionOct 27, 2021
Study CompletionJan 31, 2023
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 6.7 years ago

Interventions

Ridge preservation using L-PRF/FDBA layered techniqueprocedure

Atraumatic tooth extraction following by socket grafting using L-PRF/FDBA layered technique

Ridge preservation using L-PRF/FDBAprocedure

Atraumatic tooth extraction following by socket grafting using L-PRF/FDBA

Ridge preservation using L-PRFprocedure

Atraumatic tooth extraction following by socket grafting using L-PRF