CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 12 enrolled
Drug / intervention
Bupropion +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04135937
NCT04135937Phase 4Completed

A Personalized mHealth Approach to Smoking Cessation for Veterans Living With HIV (CDA 17-005)

VA Office of Research and Development·interventional·Posted Oct 23, 2019·Updated Jul 27, 2023

In Brief

A Phase 4 clinical trial evaluating Bupropion, Varenicline, and 3 other interventions for Human Immunodeficiency Virus and Smoking. Completed, enrolled 12 participants across 1 site.

Detailed Summary

Smoking is a significant cause of damage to health and quality of life specifically for Veterans with human immunodeficiency virus (HIV). Smoking cessation interventions for this population are lacking. The primary aim of this project is to explore smoking cessation treatment preferences among Veteran smokers living with HIV. The study team will refine the design and content of a smoking cessation treatment for Veteran smokers living with HIV. The intervention uses mobile health and telehealth technology to personalize smoking cessation counseling and medications and provide relapse prevention text messaging.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedOct 23, 2019
Enrollment StartNov 18, 2019
Primary CompletionJul 15, 2021
Study CompletionNov 10, 2021
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.7 years ago

Interventions

Bupropiondrug

Smoking cessation pharmacotherapy prescribed in accordance with package insert.

Vareniclinedrug

Smoking cessation pharmacotherapy prescribed in accordance with package insert.

Cognitive Behavioral Therapybehavioral

Behavioral intervention; modules include identifying reasons for quitting, setting a quit date, breathing relaxation technique, identifying smoking triggers, identifying social support, and education about relapse prevention

Nicotine Replacement Therapydrug

Participants may be prescribed single-formulation NRT (i.e., nicotine patch) or dual NRT (patch + rescue method such as nicotine gum, inhaler, or lozenges).

Relapse Prevention Text Messagingbehavioral

Participants will be invited to utilize SmokefreeVET, a mobile text messaging service for military Veterans trying to quit smoking. The 6- to 8-week program provides 24/7 encouragement, advice, and tips to help smokers quit smoking and stay quit.