CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Application of platelet rich plasma in chronic wounds of diabetic originother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04145154
NCT04145154N/ACompleted

Effect of the Rich Plasma in Growth Factors on the Cicatrization of Diabetic Ulcers

Universidad de Guanajuato·interventional·Posted Oct 30, 2019·Updated Nov 4, 2022

In Brief

A clinical study evaluating Application of platelet rich plasma in chronic wounds of diabetic origin for Chronic Skin Ulcer and 2 related conditions. Completed, enrolled 16 participants across 1 site.

Detailed Summary

Diabetic foot is defined by World Health Organization as a syndrome in which the presence of neuropathy, ischemia and infection cause tissue damage or ulcers from minor trauma. This condition can be controlled in its early stages with conservative treatment, which is effective in preventing infections and amputations. However, even with the new knowledge acquired and the development of new therapies, the specialist often faces wounds that do not improve despite the proper treatment, so therapies have been sought to help the healing of these Ulcers. Growing evidence suggests that healing of chronic diabetic foot ulcers depends on growth factors and that the therapeutic use of these in wounds has the potential to accelerate their healing in conjunction with wound care Conventional. This study evaluates the effect of plasma rich in autologous growth factors on healing chronic ulcers of diabetic origin. This is a randomized clinical trial that evaluates two study groups. Control group in which advanced weekly healing will be performed while the post-advanced healing study group will be performed the intradermal application of plasma rich in growth factors. These manoeuvres will be performed once a week for four weeks and at the end of the study the results in both groups will be checked. Both groups will also evaluate, frequency and intensity of pain, quality of life, histological changes in ulcers and metabolic evaluation

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesMexico
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedOct 30, 2019
Enrollment StartJun 5, 2018
Primary CompletionApr 30, 2020
Study CompletionMay 28, 2020
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 6.7 years ago

Interventions

Application of platelet rich plasma in chronic wounds of diabetic originother

Application of plasma rich in autologous growht factors after advanced healing