CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 424 enrolled
Drug / intervention
Lebrikizumab +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04146363
NCT04146363Phase 3Completed

A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of Lebrikizumab in Patients With Moderate to Severe Atopic Dermatitis

Eli Lilly and Company·interventional·Posted Oct 31, 2019·Updated Nov 30, 2022

In Brief

A Phase 3 clinical trial evaluating Lebrikizumab and Placebo for Atopic Dermatitis. Completed, enrolled 424 participants across 94 sites in 10 countries.

Detailed Summary

This is a randomized, double-blind, placebo-controlled, parallel-group study which is 52 weeks in duration. The study is designed to confirm the safety and efficacy of lebrikizumab as monotherapy for treatment of moderate-to-severe atopic dermatitis utilizing a 16-week induction treatment period and a 36-week long-term maintenance treatment period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Canada, Estonia, France, Latvia, Lithuania, Poland, South Korea, Spain, United States
CollaboratorsDermira, Inc.

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedOct 31, 2019
Enrollment StartSep 24, 2019
Primary CompletionJun 21, 2021
Study CompletionMay 3, 2022
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.7 years ago

Interventions

Lebrikizumabbiological

Subcutaneous injection

Placeboother

Subcutaneous Injection