At a glance
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Postoperative Pain Control in Septum and Sinus Surgery: A Novel Approach.
In Brief
A Phase 4 clinical trial evaluating Acetaminophen 325 mg Oral Tablet, Acetaminophen 650 mg Oral Tablet, and 2 other interventions for Post-operative Pain and Sinus Surgery. Completed, enrolled 65 participants across 1 site.
Detailed Summary
This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients. Participants will be randomized like a flip of a coin to either the standard of care pain treatment of acetaminophen 325 mg as needed for pain plus opiates (acetaminophen/hydrocodone) as needed for breakthrough pain; OR to the study arm of acetaminophen 650 mg every 6 hours plus opiates (Oxycodone)as needed for breakthrough pain.
Study Details
Timeline
Interventions
Standard of Care Acetaminophen 325 mg every 6 hours as needed for pain
Acetaminophen 650 mg scheduled every 6 hours round the clock for pain
Oxycodone 5 mg every 4 hours as needed for breakthrough pain
Acetaminophen 325 mg/ Hydrocodone 7.5 mg oral tablet every 4 hours as needed for breakthrough pain