CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 489 enrolled
Drug / intervention
Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04154631
NCT04154631N/ACompleted

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health Part 1: Implementation

University of California, Berkeley·interventional·Posted Nov 6, 2019·Updated Oct 27, 2025

In Brief

A clinical study evaluating Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), and 1 other intervention for Sleep Disorder and Circadian Dysregulation. Completed, enrolled 489 participants across 10 sites.

Detailed Summary

The sleep disturbance commonly experienced by individuals with a severe mental illness (SMI) reduces these individuals' capacity to function and contributes to key symptoms. This study will test the effects of a sleep treatment that has been adapted using theory, data and stakeholder inputs to improve the fit for SMI patients treated in community mental health centers (CMHCs), relative to the standard treatment. The investigators will also determine if the adapted and standard versions can improve sleep, improve functioning and reduce symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedNov 6, 2019
Enrollment StartJan 8, 2020
Primary CompletionDec 19, 2023
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 6.7 years ago

Interventions

Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)behavioral

TranS-C is a psychosocial treatment designed to improve sleep and circadian functioning. It is a modular, psychosocial, skills-based approach. In this study, two version of TranS-C will be tested: Standard and Adapted.

Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)behavioral

The Adapted version was derived from Standard TranS-C. It was developed to improve the fit of the treatment with the CMHC context.

Usual Care Delayed Treatmentother

Usual care in the partner CMHCs typically starts with a case manager who co-ordinates care and refers each client for a medication review and to various rehabilitation programs (e.g., health care, housing, nutrition, finding a job, peer monitoring).