CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 26 enrolled
Drug / intervention
Galcanezumabdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04158752
NCT04158752Phase 4Completed

Anti-CGRP Neutralizing Antibody for Modulation of Neurogenic Inflammation in Trigeminal and Glossopharyngeal Pain Associated With Small Fiber Neuropathy/Fibromyalgia

Duke University·interventional·Posted Nov 12, 2019·Updated Feb 2, 2026

In Brief

A Phase 4 clinical trial evaluating Galcanezumab for Trigeminal Neuralgia and Glossopharyngeal Neuralgia. Completed, enrolled 26 participants across 1 site.

Detailed Summary

The investigators will treat patients (targeting enrollment of n=20) who suffer from trigeminal or glossopharyngeal nerve pain in the context of painful small fiber neuropathy. The primary pain-related objective is reduction of pain and reduced use of rescue and other anti-pain medications. Another goal is to monitor and confirm the safety profile established in the migraine population, during previous Phase 3 trials.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedNov 12, 2019
Enrollment StartJul 24, 2020
Primary CompletionJan 4, 2023
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 6.6 years ago

Interventions

Galcanezumabdrug

Injection of study drug at 3 timepoints (day 30, day 60, day 90)