At a glance
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QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
In Brief
A clinical study evaluating Real TBS to the vmPFC and Sham cTBS to the vmPFC for Smoking and 6 related conditions. Completed, enrolled 40 participants across 1 site.
Detailed Summary
Cigarette smoking constitutes the greatest preventable cause of mortality and morbidity in the US. The most critical period for long term success of smoking cessation appears to be in the first 7 days after the quit date. A metaanalysis of 3 pharmacotherapy trials revealed that abstinence during the first 7 days was the strongest predictor of 6 month outcomes (n=1649; Odds ratio: 1.4, P \<0.0001; Ashare et al. 2013). Prodigious relapse rates during this first week of smoking cessation are likely due to behavioral and neurobiological factors that contribute to high cue-associated craving and low executive control over smoking. The long term goal of the research is to develop evidence-based transcranial magnetic stimulation protocols to facilitate abstinence during this critical period.
Study Details
Timeline
Interventions
This will be delivered with the Magventure Magpro system; active sham coil (double blinded)
The MagVenture MagPro system has an integrated active sham that uses two surface electrodes placed on the skin beneath the coil.