At a glance
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Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
In Brief
A Phase 4 clinical trial evaluating Dextenza and Prednisolone Acetate for Keratoconus, Unstable and 2 related conditions. Completed, enrolled 20 participants across 1 site.
Detailed Summary
There is no standard of care medication regimen for the management of pain and inflammation post-corneal crosslinking (CXL), although most cornea specialists agree on use of an antibiotic and steroid eye drop in the immediate postoperative period. However, steroid tapering schedule and use of additional topical non-steroidal anti-inflammatory (NSAID) eyedrops vary amongst practitioners. The goal of this study is to compare postoperative pain scores between patients receiving a tapering dose of topical steroids over 1-month post-CXL, versus those receiving an intracanalicular dexamethasone insert.
Study Details
Timeline
Interventions
Placement of intracanalicular dexamethasone insert for post-crosslinking inflammation and pain
post-crosslinking eye drop prednisolone acetate given in a tapering schedule over 1 month