CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 12 enrolled
Drug / intervention
dasiglucagon +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04172441
NCT04172441Phase 3Completed

A Randomized Trial in 2 Parts: Double-Blind, Placebo-Controlled, Crossover Part 1 and Open-label Part 2, Evaluating the Efficacy and Safety of Dasiglucagon for the Treatment of Children With Congenital Hyperinsulinism

Zealand Pharma·interventional·Posted Nov 21, 2019·Updated Mar 14, 2025

In Brief

A Phase 3 clinical trial evaluating dasiglucagon and Placebo for Congenital Hyperinsulinism. Completed, enrolled 12 participants across 6 sites in 4 countries.

Detailed Summary

The objective of the trial is to evaluate the efficacy of dasiglucagon in reducing glucose requirements in children with persistent congenital hyperinsulinism (CHI) requiring continuous intravenous (IV) glucose administration to prevent/manage hypoglycemia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Israel, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedNov 21, 2019
Enrollment StartJun 19, 2020
Primary CompletionFeb 17, 2022
Study CompletionMar 7, 2022
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.6 years ago

Interventions

dasiglucagondrug

Glucagon analogue

Placebodrug

Placebo for dasiglucagon