CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 119 enrolled
Drug / intervention
Brexpiprazole +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04174365
NCT04174365Phase 3Completed

A Phase 3, Multicenter, Randomized, Double-blind, Placebo Controlled Trial of Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder

Otsuka Pharmaceutical Development & Commercialization, Inc.·interventional·Posted Nov 22, 2019·Updated Aug 28, 2025

In Brief

A Phase 3 clinical trial evaluating Brexpiprazole and Placebo for Irritability Associated With Autism Spectrum Disorder (ASD). Completed, enrolled 119 participants across 1 site.

Detailed Summary

The purpose of this study is to find out about the potential benefits and safety of brexpiprazole in children and adolescent participants, aged 5 to 17, with irritability associated with autism spectrum disorder.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsH. Lundbeck A/S

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedNov 22, 2019
Enrollment StartOct 30, 2019
Primary CompletionAug 8, 2022
Study CompletionSep 9, 2022
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 6.6 years ago

Interventions

Brexpiprazoledrug

Oral tablet; take once daily

Placebodrug

Administered orally daily for up to Week 8.