CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 556 enrolled
Drug / intervention
Orsiro DESdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04175626
NCT04175626N/ACompleted

BIOTRONIK - A Prospective Multicenter Study to Confirm the SaFety and Effectiveness of the Orsiro SiroLimus Eluting Coronary Stent System in the Treatment Of Subjects With up to Three De Novo or Restenotic Coronary Artery Lesions - VII

Biotronik, Inc.·observational·Posted Nov 25, 2019·Updated Feb 27, 2026

In Brief

An observational study evaluating Orsiro DES for Coronary Artery Disease and 5 related conditions. Completed, enrolled 556 participants across 33 sites.

Detailed Summary

The objective of this post-approval study is to confirm that the clinical performance of the Orsiro stent in a real-world setting is similar to the clinical performance observed for Orsiro in the BIOFLOW-V Investigational Device Exemption pivotal trial, as a condition of the US Food and Drug Administration (FDA) approval (P170030).

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedNov 25, 2019
Enrollment StartJan 24, 2020
Primary CompletionJan 12, 2022
Study CompletionJan 8, 2026
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 6.6 years ago

Interventions

Orsiro DESdevice

Orsiro is a device/drug combination product composed of two components, a device (coronary stent system including a cobalt chromium stent platform), and a drug product (a formulation of sirolimus) contained in a bioabsorbable polymer coating.