At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 100 enrolled
Drug / intervention
Simvastatin 20 mg +1 moredrug
Likely dose
Simvastatin 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Combination of Methotrexate and Statins With Methotrexate Alone as an Anti-inflammatory Agent in the Treatment of Rheumatoid Arthritis.
In Brief
A Phase 4 clinical trial evaluating Simvastatin 20 mg and Methotrexate 10 mg for Arthritis, Rheumatoid. Completed, enrolled 100 participants across 1 site.
Detailed Summary
The objective of the study is to compare the efficacy of combination of Methotrexate and Statins with Methotrexate alone in the treatment of Rheumatoid Arthritis. It is hypothesized that adding statins to methotrexate for treatment of rheumatic arthritis will significantly suppress the disease activity as compared to methotrexate alone.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsArthritis, Rheumatoid
CountriesPakistan
Collaborators--
Timeline
Phase 4CompletedFinished
201820192020202120222023202420252026
Enrollment StartSep 2017
Primary CompletionDec 2018
First PostedNov 2019
TodayJul 2026
First PostedNov 26, 2019
Enrollment StartSep 1, 2017
Primary CompletionDec 14, 2018
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 6.6 years ago
Interventions
Simvastatin 20 mgdrug
improvement of disease activity
Methotrexate 10 mgdrug
improvement of disease activity