CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 137 enrolled
Drug / intervention
Vitamin D +1 moredrug
Likely dose
Vitamin D 50,000IUfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04177758
NCT04177758Phase 4Completed
CompareCT.gov

A Prospective, Tripled-Blinded, Randomized Controlled Trial Evaluating Vitamin D3 Supplementation on Post-Operative Functional and Clinical Outcomes Following Total Knee Arthroplasty

Rush University Medical Center·interventional·Posted Nov 26, 2019·Updated Apr 12, 2023

In Brief

A Phase 4 clinical trial evaluating Vitamin D and Control for Knee Osteoarthritis. Completed, enrolled 137 participants across 1 site.

Detailed Summary

The aim of this study is to determine if vitamin D supplementation is associated with differences in short-term recovery in patients following total knee arthroplasty compared to patients who do not receive supplementation. If so, vitamin D supplementation has the potential to become widely incorporated into the routine care for patients undergoing knee replacements.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedNov 26, 2019
Enrollment StartFeb 1, 2020
Primary CompletionOct 8, 2021
Study CompletionMar 1, 2022
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.6 years ago

Interventions

Vitamin Ddrug

Patients randomized to the experimental arm of the study will receive 50,000IU of vitamin D3 following surgery and asked to take the medication orally following surgery.

Controldrug

Patients randomized to the control will receive a placebo