At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Personalized Treatment Algorithms for Difficult-to-treat Asthma: Bench to Community
In Brief
A Phase 2 clinical trial evaluating Cholecalciferol, antihistamine, and 4 other interventions for Asthma in Children. Completed, enrolled 21 participants across 1 site.
Detailed Summary
Asthma is a common, complex and costly chronic condition. Moreover, asthma is heterogeneous in terms of treatment response. This heterogeneity contributes to the difficulty in both studying and treating asthma. This is a pilot study to improve health outcomes in youths with difficult to treat asthma with ongoing symptoms and healthcare utilization despite medium to high doses of inhaled corticosteroids. Asthma heterogeneity in both disease pathophysiology and treatment response contributes to the difficulty in both studying and managing asthma. In order to begin to develop personalized algorithms for patients, investigators need to model novel biomarkers and other factors that contribute to individual differences in asthma outcome and test other factors that contribute to individual differences in asthma outcome and test personalized treatment strategies.
Study Details
Timeline
Interventions
Oral administration
Oral administration
Oral administration
Topical
Nasal spray
Study participants asthma controller medication may be increased based off of their asthma control and the recommendation of the personalized plan.