At a glance
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Diaphragm Stimulation After Human Spinal Cord Injury: Effects on Respiratory Neural Drive and Function
In Brief
An observational study evaluating Diaphragm Pacing for Cervical Spinal Cord Injury. Completed, enrolled 6 participants across 1 site.
Detailed Summary
This project will evaluate the effects of intramuscular diaphragm stimulation (pacing) and test the hypothesis that diaphragm pacing enhances neuromuscular diaphragm activation and respiratory function in adults with cervical spinal cord injuries (C-SCIs). The investigators will test the hypothesis by recording activity of the diaphragm from intramuscular pacing electrodes and conduct respiratory assessments in adults with intramuscular diaphragm pacing electrodes following acute, traumatic C-SCIs.
Study Details
Timeline
Interventions
Intramuscular stimulation of the diaphragm, or diaphragm "pacing' is achieved by laparoscopic placement of stimulation wires into each hemidiaphragm. Phrenic motor points on the diaphragm are mapped to optimize electrode placement. The electrodes are threaded into the diaphragm muscle and wire leads are externalized and attached to a stimulation controller.