CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 171 enrolled
Drug / intervention
ID/LAB +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04180020
NCT04180020N/ACompleted
CompareCT.gov

Coordinating Opioid Use Treatment Through Medical Management With Infection Treatment (Project COMMIT)

Yale University·interventional·Posted Nov 27, 2019·Updated Apr 3, 2025

In Brief

A clinical study evaluating ID/LAB and TAU for Opioid-use Disorder. Completed, enrolled 171 participants across 3 sites.

Detailed Summary

This study seeks to test a new model of care (ID/LAB) in which opioid use disorder (OUD) is managed by infectious disease (ID) specialists and hospitalists concurrent with management of the OUD-related infections, using long-acting injectable buprenorphine (LAB), followed by referral as soon as possible after hospital discharge to community resources for long term treatment of OUD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOpioid-use Disorder
CountriesUnited States
CollaboratorsNational Center for Advancing Translational Sciences (NCATS)

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedNov 27, 2019
Enrollment StartAug 18, 2020
Primary CompletionFeb 6, 2024
Study CompletionApr 25, 2024
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 6.6 years ago

Interventions

ID/LABother

ID/LAB is the new model in which OUD is managed by Infectious Disease (ID) specialists and/or Hospitalists concurrent with management of the infectious diseases, using long-acting injectable buprenorphine (LAB).

TAUother

TAU is designed to systematize what is the current practice at the participating hospitals and in most U.S. hospitals while offering a minimum standard of care. TAU will constitute recommendation for MOUD initiation and consultation for addiction medicine when available; in practice, it is typically detoxification from opioids and referral to community-based addiction treatment after hospital discharge.