At a glance
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Mid-Q Response Study
In Brief
A clinical study evaluating aCRT ON and aCRT OFF for Heart Failure and 5 related conditions. Completed, enrolled 177 participants across 61 sites in 10 countries.
Detailed Summary
The Mid-Q Response study is a prospective, multi-center, randomized controlled, interventional, single-blinded, post-market study. The purpose of the Mid-Q Response study is to test the hypothesis that the AdaptivCRT (aCRT) algorithm is superior to standard CRT therapy regarding patient outcomes in CRT indicated patients with moderate QRS duration, preserved atrioventricular (AV) conduction and left bundle branch block (LBBB). The study will be executed at approximately 60 centers in Asia. The subjects will be randomly assigned in a 1:1 ratio to the aCRT ON (Adaptive Bi-V and LV) group or the aCRT OFF (Nonadaptive CRT) group. The primary objective is to test the hypothesis that aCRT ON increases the proportion of patients that improve on the Clinical Composite Score (CCS) compared to aCRT OFF at 6 months of follow-up.
Study Details
Timeline
Interventions
CRT device with AdaptivCRT enabled
CRT device with AdaptivCRT disabled