At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Multicenter Randomized Double-Blind Control Trial Evaluating the Utility of Continuous Positive Airway Pressure (CPAP) in the Treatment of High Altitude Pulmonary Edema (HAPE)
In Brief
A clinical study evaluating CPAP mask system, Nifedipine 30 MG, and 1 other intervention for Continuous Positive Airway Pressure and High Altitude Pulmonary Edema. Completed, enrolled 64 participants across 1 site.
Detailed Summary
The primary objective is to evaluate the efficacy of continuous positive pressure on resolution of high-altitude pulmonary edema vs high flow oxygen. The secondary objective is to derive an incidence of high-altitude pulmonary edema based on the elevation and timing from which the subject arrives. Additionally, in a convenience sample of the base study population, an ultrasound evaluation for the presence of B lines in the lungs will be conducted after 2 hours.
Study Details
Timeline
Interventions
Intervention group will receive 15cm of H2O of positive end expiratory pressure
All participants will receive this intervention
Placebo group will receive high flow oxygen via altered CPAP mask system without providing any positive end expiratory pressure