CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 59 enrolled
Drug / intervention
Silver Diamine Fluoridedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04186663
NCT04186663Phase 2Completed
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Pharmacokinetics of Advantage Arrest in Children

Advantage Silver Dental Arrest, LLC·interventional·Posted Dec 5, 2019·Updated Mar 10, 2022

In Brief

A Phase 2 clinical trial evaluating Silver Diamine Fluoride for Dental Caries. Completed, enrolled 59 participants across 1 site.

Detailed Summary

The purpose of this study is to characterize basic PK parameters (Cmax, t1/2, AUC) in healthy children to contribute to evidence for the safety of Advantage Arrest, consistent with Guidance for Industry--Exposure--Response Relationships (April 2003).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDental Caries
CountriesUnited States
CollaboratorsUniversity of California, San Francisco

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedDec 5, 2019
Enrollment StartAug 1, 2019
Primary CompletionMar 31, 2020
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 6.6 years ago

Interventions

Silver Diamine Fluoridedrug

38% aqueous silver diamine fluoride \[Ag(NH3)\]2F, CAS RN 33040-28-7