CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Facial Microexpression Trainingbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04187326
NCT04187326N/ACompleted

Feed Forward Visual System Function In High Trait Anxiety

University of Massachusetts, Worcester·interventional·Posted Dec 5, 2019·Updated Sep 4, 2025

In Brief

A clinical study evaluating Facial Microexpression Training for Anxiety. Completed, enrolled 23 participants across 1 site.

Detailed Summary

High trait anxiety, a stable personality trait, is a risk factor for psychiatric disorders. Individuals with high trait anxiety have difficulty differentiating safety from threat, including visual information like emotional faces. This study aims to characterize visual system function in high trait anxiety. A portion of this study involves an intervention. For the intervention portion, a subset of participants will be asked to return for a lab visit upon completing the first portion of the study (multimodal magnetic resonance imaging (MRI) scan). During this follow up visit, participants will complete a computer task that involves looking at faces and identifying emotions. Participants will complete this task either six months or twelve months after their MRI scan visit. Results from this research have the potential to inform novel therapies that target the visual system in individuals at risk for the development of psychiatric disorders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedDec 5, 2019
Enrollment StartMar 1, 2021
Primary CompletionMar 15, 2024
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 6.6 years ago

Interventions

Facial Microexpression Trainingbehavioral

The METT is a well-validated task designed to improve perception of subtle changes in facial expressions, termed microexpressions. Participants with high trait anxiety will return to the lab approximately six months post scan visit to complete this computer-based task. They will receive feedback during the task on their accuracy.