CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 71 enrolled
Drug / intervention
Experimental: SNF472 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04195906
NCT04195906Phase 3Completed

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of SNF472 When Added to Background Care for the Treatment of Calciphylaxis

Sanifit Therapeutics S. A.·interventional·Posted Dec 12, 2019·Updated Feb 20, 2024

In Brief

A Phase 3 clinical trial evaluating Experimental: SNF472, Placebo Comparator: Placebo, and 1 other intervention for Calciphylaxis and Calcific Uremic Arteriolopathy. Completed, enrolled 71 participants across 58 sites in 6 countries.

Detailed Summary

The primary objectives are to assess the efficacy, safety, and tolerability of SNF472 compared to placebo when added to background care for the treatment of calciphylaxis (CUA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Germany, Poland, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedDec 12, 2019
Enrollment StartFeb 12, 2020
Primary CompletionOct 24, 2022
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 6.6 years ago

Interventions

Experimental: SNF472drug

Administered 3 times weekly by intravenous infusion through the hemodialysis machine in conjunction with the subject's hemodialysis sessions for 12 weeks

Placebo Comparator: Placebodrug

Administered 3 times weekly by intravenous infusion through the hemodialysis machine in conjunction with the subject's hemodialysis sessions fo 12 weeks

Experimatenl SNF472 (Open-label)drug

Administered 3 times weekly by intravenous infusion through the hemodialysis machine in conjunction with the subject's hemodialysis sessions for 12 weeks